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Drug-resistant TB
WHO and PATH publish updated MDR-TB Planning Toolkit

The World Health Organization (WHO) and PATH have published a new version of the MDR-TB Planning Toolkit. The toolkit, developed with funding from the United States Agency for International Development, is designed to help countries develop or strengthen their national response to drug-resistant tuberculosis.

Published
05 October 2012
From
Stop TB Partnership
TB treatment
Launch of the Good Participatory Practice Guidelines for TB Drug Trials

The Stakeholder and Community Engagement Workgroup of the Critical Path to TB Drug Regimens initiative launches guidelines that will facilitate the involvement of communities and participants in the conduct of TB drug trials.

Published
04 October 2012
From
Critical Path to TB Drug Regimens
Drug-resistant TB
TB drug trial yields gains in drug-resistant disease treatment

A study following patients who had participated in a trial of a potential new treatment for drug-resistant tuberculosis has shown heartening results, with nearly three-quarters of patients who took the medicine for six months or longer showing “favorable outcomes” — cured or completed treatment – according to a study published in the European Respiratory Journal.

Published
02 October 2012
From
Science Speaks
Drug-resistant TB
In Romania, chance determines whether drug-resistant TB patients survive

In Romania, all drug-resistant TB cases are reviewed by a commission of doctors. The Commission members ultimately make a choice on who lives and who dies. This is an impossible choice described by one doctor as verging on malpractice—the knowing condemnation of patients to inferior medication because of budget constraints.

Published
25 September 2012
From
AlertNet
TB treatment
Sanofi and TB Alliance Announce Collaboration to Accelerate New Treatments Against Tuberculosis

Sanofi and the Global Alliance for TB Drug Development (TB Alliance) announced today a new research collaboration agreement to accelerate the discovery and development of novel compounds against tuberculosis (TB), a deadly infectious disease that resulted in almost 1.5 million deaths worldwide1 in 2010.

Published
21 September 2012
From
TB Alliance
Drug-resistant TB
Oxyphenbutazone can kill drug resistant TB

An off-patent anti-inflammatory drug that costs around two cents for a daily dose in developing countries has been found by researchers at Weill Cornell Medical College to kill both replicating and non-replicating drug resistant tuberculosis in the laboratory -- a feat few currently approved TB drugs can do, and resistance to those is spreading.

Published
11 September 2012
From
News-Medical Net
Drug-resistant TB
HIV is a risk factor for acquired resistance to key second-line anti-TB drugs

Infection with HIV is a major risk factor for the development of resistance to key second-line anti-tuberculosis (TB) drugs, US investigators report in the online edition of

Published
06 September 2012
By
Michael Carter
Drug-resistant TB
Janssen-Cilag International NV (Janssen) Submits European Marketing Authorisation Application for Investigational Multi-Drug Resistant Tuberculosis Treatment Bedaquiline

If approved, bedaquiline (Ba-DA-qui-lin) could be one of the first drugs with a new mechanism of action for tuberculosis (TB) in more than 40 years and one of the first ever to be specifically indicated for MDR-TB.

Published
03 September 2012
From
Janssen-Cilag press release
Drug-resistant TB
International study finds "worrying" levels of XDR-TB

Results of an international study published in The Lancet show that 7% of people receiving second-line treatment for tuberculosis (TB) have extensively drug-resistant TB (XDR-TB). The investigators describe

Published
31 August 2012
By
Michael Carter
Drug-resistant TB
Alarming levels of drug-resistant TB found worldwide

In a large international study published in the Lancet medical journal on Thursday, researchers found rates of both multi drug-resistant TB (MDR-TB) and extensively drug-resistant TB (XDR-TB) were higher than previously thought and were threatening global efforts to curb the spread of the disease.

Published
30 August 2012
From
Reuters
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